Diagnostic Value of a Protocolized In-Depth Evaluation of Pediatric Bone Marrow Failure: A Multi-Center Prospective Cohort Study
BackgroundSevere multilineage cytopenia in childhood caused by bone marrow failure (BMF) often represents a serious condition requiring specific management.Patients are at risk for invasive infections Collections and bleeding complications.Previous studies report low rates of identifiable causes of pediatric BMF, rendering most patients with a desc